INFLUENCE OF GENETIC COPY NUMBER VARIANTS OF THE HUMAN GLUT3 GLUCOSE TRANSPORTER GENE SLC2A3 ON PROTEIN EXPRESSION, GLYCOLYSIS AND RHEUMATOID ARTHRITIS RISK: A GENETIC REPLICATION STUDY

Objectives: The gene encoding glucose transporter 3 (GLUT3, SLC2A3) is present in the human population at variable copy number.An overt disease phenotype of SLC2A3 copy number variants has not been reported; however, deletion of SLC2A3 has been previously reported to protect carriers from rheumatoid arthritis, implicating GLUT3 as a therapeutic tar

The professional education starts in infancy, since the basic school education already comprises some abilities and some knowledge required for the professional areas.In fact, school represents the main institution to mediate the transmission of systematized knowledge, contributing to the development of the logical thinking.Piaget (1972) states tha

Introduction: Local treatment of the airways and lung parenchyma has Beach Tent been used in clinical practice for several years for a variety of diseases.Methods: A variety of endoscopic tools for local treatment exist, especially for treating malignancies.Using these endoscopic tools, one can administer drugs specifically designed for the airways

Abstract Leaf copyright Oil rust, caused by Puccinia triticina Eriksson (Pt), is one of the most severe foliar diseases of wheat.Breeding for leaf rust resistance is a practical and sustainable method to control this devastating disease.Here, we report the identification of Lr47, a broadly effective leaf rust resistance gene introgressed into wheat